Category: Post-translational Modifications

Panc02-mTrop2 cells proliferated 2.7 times faster than Panc02-GFP cells at day 5. adenocarcinoma cells overexpressing human Trop2. Conclusions These findings demonstrate some of the pathogenic effects mediated by mTrop2 expression on cancer cells and the importance of targeting this cell surface glycoprotein. This study also provides the first indication of a molecular signaling pathway activated…
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Thus, the balance between ADAM-17 and TIMP-3 expression can control the inflammation process. and NO), TNF-has destructive effects on sperm [8], and the TNF-from the pro-TNF-molecule. Since ADAM-17 was found to be inhibited by tissue inhibitors of metalloproteinases-3 (TIMP-3); TIMP-3 are important factors involved in the regulation of the inflammatory process and the disease progression…
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