Category: Phosphoinositide 3-Kinase

protease inhibitor

Both caveolae and T-tubules represent membrane systems which are continuous with the plasma membrane but have a distinct composition

Both caveolae and T-tubules represent membrane systems which are continuous with the plasma membrane but have a distinct composition. in the early development of the T-tubule system in muscle. The plasma membrane of mammalian cells is divided into a number of different structural and functional microdomains. Much recent interest has been focused on one such…
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In mice with Mx-Cre-mediated excision of floxed FN in the liver, injury still induces a robust increase in ColI, ColIII, Ltbp-1, Ltbp-3, and Ltbp-4 incorporation into the extracellular matrix [33, 34]

In mice with Mx-Cre-mediated excision of floxed FN in the liver, injury still induces a robust increase in ColI, ColIII, Ltbp-1, Ltbp-3, and Ltbp-4 incorporation into the extracellular matrix [33, 34]. We examined the expression of Fibrillin-1, Fibrillin-2, Ltbp-1, Ltbp-3 and Ltbp-4 by immunofluorescence in FN-deleted RIP-Tag tumors. pancreatic adenocarcinomas. In the nearly complete absence…
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Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression

Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression. 2014; Towner et al., 2006). Similarly to EBOV, virions of MARV are covered by the homotrimeric spikes of GP, the sole envelope viral protein responsible for cell entry. GP is a heavily…
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