2011;17:5060\5070
2011;17:5060\5070. In tumors IFN-alphaJ with obtained level of resistance to trastuzumab and pertuzumab or even to T\DM1, HER2\HER3 phosphorylation was maintained. Switching to TAS0728 led to a substantial anti\tumor effect connected with HER2\HER3 sign inhibition. No substitute receptor tyrosine kinase activation was seen in these resistant tumors. Furthermore, inside a individual\produced xenograft model produced from…
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