The pathophysiological importance of anti-Dsg autoimmunity in pemphigus has been suggested (810) from the results of experiments showing the ability of recombinant Dsg 1 and Dsg 3 constructs to absorb disease-causing antibodies from PF and PV sera, respectively (2123)
The pathophysiological importance of anti-Dsg autoimmunity in pemphigus has been suggested (810) from the results of experiments showing the ability of recombinant Dsg 1 and Dsg 3 constructs to absorb disease-causing antibodies from PF and PV sera, respectively (2123). These PV IgGs caused gross pores and skin blisters with PV-like suprabasal acantholysis and stained perilesional…
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